منابع مشابه
Translocation of inhaled ultrafine particles to the brain.
Ultrafine particles (UFP, particles <100 nm) are ubiquitous in ambient urban and indoor air from multiple sources and may contribute to adverse respiratory and cardiovascular effects of particulate matter (PM). Depending on their particle size, inhaled UFP are efficiently deposited in nasal, tracheobronchial, and alveolar regions due to diffusion. Our previous rat studies have shown that UFP ca...
متن کاملUltrafine particles in cities.
Ultrafine particles (UFPs; diameter less than 100 nm) are ubiquitous in urban air, and an acknowledged risk to human health. Globally, the major source for urban outdoor UFP concentrations is motor traffic. Ongoing trends towards urbanisation and expansion of road traffic are anticipated to further increase population exposure to UFPs. Numerous experimental studies have characterised UFPs in in...
متن کاملExtrapulmonary translocation of ultrafine carbon particles following whole-body inhalation exposure of rats.
Studies with intravenously injected ultrafine particles have shown that the liver is the major organ of their uptake from the blood circulation. Measuring translocation of inhaled ultrafine particles to extrapulmonary organs via the blood compartment is hampered by methodological difficulties (i.e., label may come off, partial solubilization) and analytical limitations (measurement of very smal...
متن کاملTranslocation of Inhaled Ultrafine Manganese Oxide Particles to the Central Nervous System
BACKGROUND Studies in monkeys with intranasally instilled gold ultrafine particles (UFPs; <100 nm) and in rats with inhaled carbon UFPs suggested that solid UFPs deposited in the nose travel along the olfactory nerve to the olfactory bulb. METHODS To determine if olfactory translocation occurs for other solid metal UFPs and assess potential health effects, we exposed groups of rats to mangane...
متن کاملCommentary: inflamed about ultrafine particles?
Ambient air pollution has been linked to exacerbation of cardiovascular disease morbidity and mortality. 1 These associations have been strikingly robust and range from the observation of coronary heart disease exacerbation within hours of exposure to an increased risk of ischaemic heart disease mortality for subjects chronically exposed to elevated concentrations of ambient particles. Two main...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 2006
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.114-a211b